Correspondence received by the Office of Indian Affairs, Central Superintendency in St. Louis, Missouri. William Clark (of Lewis and Clark fame) was the Superintendent of Indian Affairs until his death in 1838. His correspondence with Indian agents covered many topics, including small pox and other diseases, struggles between tribes, the activities of tradesmen, and the disbursement of annuities. Also included are statements showing the number of American citizens robbed or killed by Indians while engaging in the fur trade to Mexico and the Rocky Mountain region. A searchable, full-text (PDF) transcription is available under "External Links" below.
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